�Diseases, Conditions and Injuries

Laryngeal Cancer

by Rick Alan


Definition | Causes | Risk Factors | Symptoms | Diagnosis | Treatment | Prevention | Organizations

En Espa�ol (Spanish Version)

Definition

Laryngeal cancer is a disease in which cancer cells grow in the larynx. The larynx is a tube-shaped organ inside the neck that lies between the throat and the windpipe. Its main function is to produce sound for speaking.

Cancer occurs when cells in the body (in this case laryngeal cells) divide without control or order. Normally, cells divide in a regulated manner. If cells keep dividing uncontrollably when new cells are not needed, a mass of tissue forms, called a growth or tumor. The term cancer refers to malignant tumors, which can invade nearby tissues and can spread to other parts of the body. A benign tumor does not invade or spread.

The Larynx

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Causes

The cause of laryngeal cancer is unknown.

Risk Factors

A risk factor is something that increases your chances of getting a disease or condition.

  • Smoking (by far the most common high-risk behavior)
  • Excessive use of alcohol
  • Race: Black
  • Age: 55 or older
  • Sex: Male
  • Occupational exposure to certain air pollutants such as wood dust, chemicals, and asbestos
  • Gastroesophageal reflux � stomach acid that backs up into the esophagus and throat where it may come in contact with the larynx
  • Weakened immune system

Symptoms

Symptoms may include:

  • Persistent cough, hoarseness, or sore throat
  • Abnormal lump in the throat or neck
  • Difficulty swallowing
  • Pain when swallowing
  • Frequent choking on food
  • Difficulty breathing
  • Noisy breathing
  • Persistent ear pain or an unusual ear fullness or sensation in and around the skin of the ear
  • Unplanned, significant weight loss
  • Persistent bad breath

Note: These symptoms may also be caused by other, less serious health conditions. A person experiencing these symptoms should see a doctor.

Diagnosis

Your doctor will ask about your symptoms and medical history, and perform a physical exam. Tests may include:

Laryngoscopy � a thin, lighted tube inserted down the throat to examine the larynx

Biopsy � removal of a sample of laryngeal tissue to test for cancer cells

Chest X-ray � a test that uses radiation to take a picture of the larynx and nearby structures

CT Scan � a type of x-ray that uses a computer to make pictures of the inside of the larynx

MRI Scan � a test that uses magnetic waves to make pictures of the inside of the larynx

Treatment

Once laryngeal cancer is found, staging tests are performed to find out if the cancer has spread and, if so, to what extent. Treatment depends on the stage of the cancer. For early stage laryngeal cancer, either surgery or radiation alone is the most common and appropriate therapies offered. For more advanced disease, either radiation (with chemotherapy) or surgery followed by radiation is the most common treatments given.

Treatment includes:

Surgery � surgical removal of a cancerous tumor and nearby tissues, and possibly nearby lymph nodes. Surgeries for laryngeal cancer include:

Total Laryngectomy � removal of the larynx, including the vocal cords.

Partial Laryngectomy � removal of cancerous tissue while leaving as much of the vocal cords as possible.

Tracheotomy � making a hole in the neck below the larynx to help breathing. This may be temporarily necessary after surgery, or permanently placed in the case of laryngeal tumors that are too large to be removed.

Radiation Therapy (or Radiotherapy) � the use of radiation to kill cancer cells and shrink tumors. Radiation may be:

External Radiation Therapy � radiation directed at the tumor from a source outside the body

Chemotherapy - the use of drugs to kill cancer cells. Chemotherapy may be given in many forms including: pill, injection, and via a catheter. The drugs enter the bloodstream and travel through the body killing mostly cancer cells, but also some healthy cells.

Prevention

Since laryngeal cancer is extremely rare in non-smokers, the best way to prevent this type of cancer is by not smoking. Other measures you can take to reduce your risk of laryngeal cancer include:

  • Avoiding excessive alcohol use
  • Protecting yourself from toxic exposures that have been linked to laryngeal cancer

RESOURCES:

American Cancer Society
http://www.cancer.org/

CancerCare
http://www.cancercare.org/

National Cancer Institute
http://www.nci.nih.gov

SOURCES:

American Cancer Society

The Merck Manual of Medical Information, Simon and Schuster;2000.

National Cancer Institute

Triage Reviewed by EBSCO Medical Review Board in September 2005


Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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